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Democrats maintain control of Senate

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The results were a bitter loss for the GOP and are certain to prompt questions about the promise and peril of the tea party movement that just two years ago delivered a takeover of the House to the GOP. In 2010, three tea party Senate candidates in Nevada, Delaware and Colorado cost Republicans seats they were favored to win. On Tuesday, a tea party-backed candidate in Indiana denied the GOP a seat that the party had been favored to win, while Fischer and tea party-backed Ted Cruz of Texas prevailed in their races.

In a sober statement, Sen. John Cornyn, R-Texas, chairman of the National Republican Senatorial Committee, said the GOP has work to do.

"We have a period of reflection and recalibration ahead for the Republican Party. While some will want to blame one wing of the party over the other, the reality is candidates from all corners of our GOP lost tonight," Cornyn said, though he added that the party's "conservative vision is the right one to secure a stronger America for future generations."

Democratic Rep. Joe Donnelly edged out tea party-backed Indiana state treasurer Richard Mourdock in a race rocked by the Republican candidate's awkward remark that pregnancy resulting from rape is "something God intended."

Mourdock also upset some Indiana voters for his decision to sue to stop the federal auto bailout of Chrysler, which means jobs building transmissions to thousands in Kokomo. And he alienated some in his own party with his divisive win over six-term Sen. Richard Lugar in the May GOP primary. Lugar refused to campaign for him.

In Massachusetts, Democrat Elizabeth Warren knocked out Republican Sen. Scott Brown, who had stunned the political world in January 2010 when he won the late Sen. Edward M. Kennedy's seat. The strong Democratic tilt in the state and President Barack Obama's easy win over former Gov. Mitt Romney helped the consumer advocate in her bid.

The Massachusetts race was one of the most expensive in the country — $68 million — even though both candidates agreed to bar outside spending.

In Missouri, Democratic Sen. Claire McCaskill was considered the most vulnerable incumbent, but Republican Rep. Todd Akin severely damaged his candidacy in August when he said women's bodies have ways of avoiding pregnancy in instances of "legitimate rape." GOP leaders, including Romney, called on him to abandon the race. Akin stayed in.

Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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