LOS ANGELES – Lance Armstrong has agreed to a tell-all interview with Oprah Winfrey where he will address allegations that he used performance-enhancing drugs during his cycling career.

According to a release posted on Oprah's website Tuesday, it's the first interview with Armstrong since his athletic career crumbled under the weight of a massive report by USADA detailing allegations of drug use by the famous cyclist and teammates on his U.S. Postal Service teams.

It's unclear whether the interview at Armstrong's home in Austin, Texas, has already been taped. Nicole Nichols, a spokeswoman for Oprah Winfrey Network & Harpo Studios, declined comment.