DETROIT (AP) — Blinding snow squalls, high winds and a slick highway led to a mile-long series of crashes in Detroit that left at least three people dead, including two children, and 20 more injured.

Michigan State Police Lt. Michael Shaw said visibility was extremely poor when the mass of crashes happened on Interstate 75 on the southwest side of the city. The injured, also including children, have been taken to hospitals, Shaw said.

A similar pileup west of Indianapolis involving more than 40 vehicles closed Interstate 70 in both directions. There was no immediate word on injuries, but the roadway was expected to be closed for several hours.